RT Book, Section
A1 Moore, Hunter B.
A1 Gonzalez, Eduardo
A1 Moore, Ernest E.
A2 Moore, Ernest E.
A2 Feliciano, David V.
A2 Mattox, Kenneth L.
SR Print(0)
ID 1141186442
T1 Trauma-Induced Coagulopathy
T2 Trauma, 8e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071847292
LK accesssurgery.mhmedical.com/content.aspx?aid=1141186442
RD 2024/04/19
AB Despite  advances  in  emergency  medical  systems  (EMS)  and  trauma  care,  deaths  from  injury  have  increased  in  the  United  States  over  the  last  decade.1  In  both  the  civilian2  and  military3  settings,  uncontrolled  hemorrhage  is  the  leading  cause  of  preventable  death  after  injury.  In  civilian  studies,  >95%  of  deaths  from  hemorrhage  occur  within  the  first  24  hours  at  a  median  time  <3  hours.2  Consequently,  there  is  intense  interest  worldwide  in  the  pathogenesis  of  trauma  induced  coagulopathy  (TIC),  and  its  early  management.  While  there  have  been  substantial  insights,  the  words  of  Mario  Stefanini  in  his  address  to  the  New  York  Academy  of  Medicine  in  19544  remain  applicable  today: