RT Book, Section A1 Irizarry, Dre A1 Odom, Stephen A2 Mazer, Laura M. A2 Lagisetty, Kiran A2 Butler, Kathryn L. SR Print(0) ID 1191195839 T1 Appendix Surgery T2 Pocket Journal Club: Essential Articles in General Surgery YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259587580 LK accesssurgery.mhmedical.com/content.aspx?aid=1191195839 RD 2024/04/20 AB Into the 18th century, descriptions of inflammatory diseases of the appendix appeared only as solitary case reports with conflicting nomenclature and an unclear natural history.1 Only in the mid-19th century, when nitrous oxide and chloroform anesthesia granted a degree of safety to laparotomy, did early operation for appendicitis gain favor.1 In contrast to these humble beginnings, appendectomy is now the most common emergency operation in the United States, with more than 300,000 appendectomies performed annually.2