TY - CHAP M1 - Book, Section TI - Long-Term Outcomes After Critical Illness A1 - Herridge, Margaret S. A1 - Cameron, Jill I. A1 - Hopkins, Ramona O. A2 - Hall, Jesse B. A2 - Schmidt, Gregory A. A2 - Kress, John P. PY - 2015 T2 - Principles of Critical Care, 4e AB - Survivors of critical illness experience important functional decrements and decreased health-related quality of life due to ICU-acquired weakness and a spectrum of other physical disabilities, neurocognitive and neuropsychological dysfunction.These morbidities may not be wholly reversible and the decrement in function may be more marked in older patients, those with a greater burden of comorbid illness or longer ICU length of stay.Poor neurocognitive outcomes have been linked to delirium, hypoxia and sedative-hypnotic use, hypoglycemia, and possibly conservative fluid management; dysfunction is similar to that of moderate traumatic brain injury and mild dementia.Approximately one-third to one-half of survivors of critical illness will develop long-term neurocognitive impairments.Early mobility during critical illness is safe and feasible.ICU multidisciplinary early mobility rehabilitation programs designed for patients who had good premorbid functional status improve functional outcome at ICU and hospital discharge. The role for these programs in less functional patients at ICU admission is unclear as is the lasting effect of this early rehabilitation intervention on longer-term outcomes.ICU self-help manual has been shown to improve physical outcomes after critical illness.ICU diaries have been shown to improve psychological outcomes in patients after critical illness.Neurocognitive rehabilitation has shown some early benefit on outcome and requires further study.Family caregivers also experience psychological morbidity and are important modifiers of patient outcome over time. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=1107715484 ER -