TY - CHAP M1 - Book, Section TI - Transfusion Medicine and Coagulation Disorders A1 - Banever, Gregory T. A2 - Ziegler, Moritz M. A2 - Azizkhan, Richard G. A2 - Allmen, Daniel von A2 - Weber, Thomas R. PY - 2014 T2 - Operative Pediatric Surgery, 2e AB - Typical transfusion thresholds include a hematocrit of 21% in asymptomatic patients, and 30% in critically ill premature neonates or patients undergoing major surgery.Patients with sickle cell disease (SCD) require strict physiologic optimization preoperatively, and close monitoring after surgery, to prevent complications.A platelet count of 50,000/mm3 is adequate for procedures such as central line placement.For massive transfusion, a blood component ratio of 1:1:1 for red blood cells (RBCs): fresh frozen plasma (FFP): platelets is recommended.Most transfusion reactions typically fall into one of 3 categories: hemolytic, febrile, and urticarial. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=1100431863 ER -