TY - CHAP M1 - Book, Section TI - Atrioventricular Canal Defect A1 - Doherty, Gerard M. PY - 2010 T2 - Quick Answers Surgery AB - • A congenital heart lesion that increases pulmonary artery (PA) blood flow• Causes left to right shunt, results in lung infection, pulmonary vascular congestion, PA hypertension, right heart failure, pulmonary vasoconstriction, pulmonary vascular obstructive disease• Eisenmenger syndrome: Increased pulmonary hypertension to such extent that left to right shunt ceases and shunt becomes right to left, requiring heart-lung transplant• Inhaled nitric oxide, oxygen, or IV tolazoline reverses PA vasoconstriction• PA band is palliative and can reduce PA flow to alleviate RV failure and progression of pulmonary hypertension• Deficiency of tissue in central region of heart (lower atrial septum-septum primum, mitral valve, tricuspid valve)• Defect in endocardial and conal tissue development• Range of defects possible• Partial AV canal defect: Septum primum atrial septal defect (ASD), deficient lower atrial septum only• Transitional AV canal defect: Intermediate form with ASD and minor deficiency in upper ventricular system• Complete AV canal defect: ASD and severe valve anomalies• Associated with left superior vena cava (SVC), additional ventricular septal defect (VSD), anomalous pulmonary venous connection, patent ductus arteriosus (PDA), tetralogy of Fallot SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/10/10 UR - accesssurgery.mhmedical.com/content.aspx?aid=58093315 ER -