TY - CHAP M1 - Book, Section TI - Chapter 54. Management of Acute Pancreatitis A1 - Clancy, Thomas E. A1 - Ashley, Stanley W. A2 - Zinner, Michael J. A2 - Ashley, Stanley W. PY - 2013 T2 - Maingot's Abdominal Operations, 12e AB - Acute pancreatitis includes a wide spectrum of disease, from mild self-limiting symptoms to a fulminant process with multiple organ failure and high mortality. Of the approximately 185,000 patients who develop acute pancreatitis each year in the United States, most experience relatively minor episodes of disease characterized by mild parenchymal edema without distant organ dysfunction and an uneventful recovery.1 Severe episodes, however, may involve a progression to extensive pancreatic necrosis, development of the systemic inflammatory response syndrome (SIRS), multiorgan failure, rapid clinical deterioration, and even death.2,3 Although the overall mortality rate with acute pancreatitis is 2–10%, this is primarily related to the 10–30% of patients with severe disease characterized by pancreatic and peripancreatic necrosis. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/18 UR - accesssurgery.mhmedical.com/content.aspx?aid=57019196 ER -