TY - CHAP M1 - Book, Section TI - Chapter 31. Appendix, Meckel's, and Other Small Bowel Diverticula A1 - Peranteau, William H. A1 - Smink, Douglas S. A2 - Zinner, Michael J. A2 - Ashley, Stanley W. PY - 2013 T2 - Maingot's Abdominal Operations, 12e AB - The first descriptions of the appendix date to the 16th century.1–3 Although sketched in the anatomic notebooks of Leonardo da Vinci around 1500, the appendix was not formally described until 1524 by da Capri4 and 1543 by Vesalius.5 Perhaps the first description of a case of appendicitis was by Fernel in 1554,6 in which a 7-year-old girl with diarrhea was treated with a large quince. Soon thereafter, she developed severe abdominal pain and died. Autopsy showed that the quince had obstructed the appendiceal lumen, resulting in appendiceal necrosis and perforation. For the next few centuries, such cases of appendicitis were typically diagnosed at autopsy. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=57013273 ER -