TY - CHAP M1 - Book, Section TI - Chapter 31. Nissen Fundoplication A1 - Lebenthal, Abraham A1 - Bueno, Raphael A2 - Sugarbaker, David J. A2 - Bueno, Raphael A2 - Krasna, Mark J. A2 - Mentzer, Steven J. A2 - Zellos, Lambros PY - 2009 T2 - Adult Chest Surgery AB - Gastroesophageal reflux disease (GERD) is caused by the chronic reflux of gastric acid from the stomach to the esophagus. This may be the result of an incompetent lower esophageal sphincter (LES) or poor gastric emptying. GERD is an anatomic and physiologic problem that may lead to surgical consultation for treatment of either the symptoms or sequelae of reflux. It was first recognized as a clinical entity in the 1930s. Today, it is the most prevalent upper gastrointestinal disorder in the Western world.1 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2019/12/12 UR - accesssurgery.mhmedical.com/content.aspx?aid=5287872 ER -