TY - CHAP M1 - Book, Section TI - Chapter 43. The Milan Cancer Institute's Landmark Clinical Trials A1 - Veronesi, Umberto A1 - Zurrida, Stefano A2 - Kuerer, Henry M. PY - 2010 T2 - Kuerer's Breast Surgical Oncology AB - A 100 years ago, breast cancer struck 1 woman in 20. Since then, breast cancer incidence has increased steadily, not only because diagnostic modalities have become more sensitive and women and physicians are more aware of the disease, but because risk factors for the disease have become more pervasive. These include proliferation of the Western-style diet with its high proportion of animal fats, earlier menarche, delayed menopause, delayed first pregnancy, and decline of breastfeeding. These factors mainly affect developed countries but are increasingly evident in emerging countries, where, unfortunately, locally advanced breast cancers are usually diagnosed. At the end of the last century, 1 woman in 10 contracted breast cancer; now the figure is 1 in 8 in developed countries.1 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=6412767 ER -