TY - CHAP M1 - Book, Section TI - Chapter 10. Chemoprevention in the Clinical Setting A1 - Soran, Atilla A1 - Vogel, Victor G. A2 - Kuerer, Henry M. PY - 2010 T2 - Kuerer's Breast Surgical Oncology AB - Breast cancer is a complex disease, resulting from the interaction of nonmodifiable factors such as an individual's genome, age at menarche, menopause, and family history; along with modifiable risk factors such as environmental, hormonal, and lifestyle factors The goal of preventing breast cancer is to identify high-risk individuals who would benefit most from preventive therapies such as chemoprevention and risk-reducing surgeries. Chemoprevention can be defined as the use of natural or synthetic chemical agents to reverse, suppress, or prevent carcinogenic progression to invasive cancer.1-5 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=6406333 ER -