TY - CHAP M1 - Book, Section TI - Chapter 83. Fulminant Hepatic Failure A1 - Kulkarni, Sanjay A1 - Cronin, David C. A2 - Hall, Jesse B. A2 - Schmidt, Gregory A. A2 - Wood, Lawrence D.H. PY - 2005 T2 - Principles of Critical Care, 3e AB - Fulminant hepatic failure (FHF) is defined as the onset of hepatic encephalopathy (HE) within 8 weeks of the onset of liver-related symptoms.Common complications in patients with FHF include encephalopathy, cerebral edema, cardiovascular instability, renal failure, and infection.Supportive management of FHF consists of (1) airway protection, (2) intracranial pressure monitoring in the sickest patients, and (3) treatment of complications and vigilance for infection.Orthotopic liver transplantation (OLT) is the definitive therapy for FHF. Extracorporeal liver support remains investigational. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2023/03/23 UR - accesssurgery.mhmedical.com/content.aspx?aid=2296376 ER -