TY  - CHAP
M1  - Book, Section
TI  - Chapter 55. Soft Tissue Infections
A1  - Conly, John
A2  - Hall, Jesse B.
A2  - Schmidt, Gregory A.
A2  - Wood, Lawrence D.H.
PY  - 2005
T2  - Principles of Critical Care, 3e
AB  - Soft  tissue  infections  characterized  by  extensive  necrosis  of  subcutaneous  tissue,  fascia,  or  muscle  are  uncommon,  but  they  require  prompt  recognition  and  urgent  surgical  treatment.The  classic  hallmarks  of  virulent  soft  tissue  infections  are  extensive  involvement  of  the  subcutaneous  tissues  and  a  relative  paucity  of  cutaneous  involvement  until  late  in  the  course  of  the  infection.Rapidly  spreading  soft  tissue  infections  present  acutely  with  severe  systemic  toxicity.Successful  management  of  these  critically  ill  patients  depends  on  prompt  diagnosis  by  clinical  and  radiologic  means.The  principles  of  management  include  fluid  resuscitation,  hemodynamic  stabilization,  a  broad-spectrum  antimicrobial  regimen,  and  early  surgical  intervention.Prompt  surgery,  in  which  a  definitive  diagnosis  is  reached  and  all  necrotic  tissue  is  débrided,  should  be  considered  the  mainstay  of  treatment.The  mortality  rate  is  highest  when  the  diagnosis  is  delayed  or  initial  surgical  treatment  is  limited.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2023/03/22
UR  - accesssurgery.mhmedical.com/content.aspx?aid=2291752
ER  -