TY - CHAP M1 - Book, Section TI - Chapter 49. Endocarditis and Other Intravascular Infections A1 - Sizemore, James M. A1 - Cobbs, C. Glenn A1 - Carr, Mark B. A2 - Hall, Jesse B. A2 - Schmidt, Gregory A. A2 - Wood, Lawrence D.H. PY - 2005 T2 - Principles of Critical Care, 3e AB - The possibility of intravascular infection should be considered in all critically ill patients with bacteremia or fungemia of uncertain origin, particularly when there are known intravascular or endocardial abnormalities or intravascular devices; fever or hemodynamic instability of unclear origin; or signs of inflammation related to an indwelling intravascular device.Blood cultures are the most important diagnostic test for this group of infections because most intravascular infections will result in persistent bacteremia or fungemia.Successful therapy often requires prolonged administration of microbicidal agents plus removal of devices.Certain microbes, including staphylococci, enterococci, aerobic gram-negative bacilli, and yeasts, are especially likely to cause intravascular infectious disease. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2023/03/23 UR - accesssurgery.mhmedical.com/content.aspx?aid=2291003 ER -