TY - CHAP M1 - Book, Section TI - Chapter 43. Surgical Treatment of Mitral Valve Endocarditis A1 - Pettersson, Gosta B. A1 - Gillinov, A. Marc A1 - Stamou, Sotiris C. A2 - Cohn, Lawrence H. PY - 2012 T2 - Cardiac Surgery in the Adult, 4e AB - Mitral valve infective endocarditis is one of the more devastating complications of heart valve disease, and, if left untreated, is universally fatal. Although the distribution of causes of mitral valve dysfunction has changed in recent years, the incidence of infective endocarditis has remained constant over the past several decades.1 Underlying rheumatic valvular disease, which was a frequent predisposing factor to infective endocarditis in the 1980s, is now rare in industrialized nations.2 Other predisposing factors more frequently encountered today include intravenous drug abuse, immunosuppression, degenerative valvular disease, intravascular prostheses and devices, hemodialysis catheters, and nosocomial infections. Several of these predisposing factors are consequences of advances that characterize modern medicine.3 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accesssurgery.mhmedical.com/content.aspx?aid=55923676 ER -