TY - CHAP M1 - Book, Section TI - Avoiding and Managing Hazards During Live Donor Nephrectomies A1 - Castillo Delgado, Carlos A A1 - Marroquin, Carlos E A2 - Molmenti, Ernesto Pompeo PY - 2023 T2 - Molmenti’s Kidney and Pancreas Transplantation: Operative Techniques and Medical Management, 2e AB - The incidence of end-stage renal disease (ESRD) has increased steadily over the last several decades. As a result, the number of patients who require renal replacement therapy for ESRD has also increased; the majority of these patients receive renal replacement therapy in the form of dialysis. Alternatively, a growing number also receive renal replacement therapy in the form of transplantation. As the dialysis population increases, so does the number of patients waiting for a transplant. Although our demand continues to increase, the organ supply has not changed appreciably over the last decades. The shortage of viable standard cadaveric organs has forced the need to innovate and improve the utilization of every possible donor organ to include use of new ex-vivo perfusion technologies,1 expansion of the use of increased risk donors to using known human immunodeficiency virus (HIV) and hepatitis C–positive organs.2,3 Despite these innovations, there remains a significant disparity between the organ supply and demand. This disparity affects our renal population the most, because more patients are surviving to go onto dialysis, and as a result the percentage of patients who are eligible for a transplant also continues to increase. This huge disparity between organ supply and demand limits our ability to transplant every eligible patient. However, in terms of kidney disease, we do have a viable option in live donation. Although it has been demonstrated that live donation is safe with an acceptable risk profile in well-selected patients, and though major complications are rare events, complications do occur. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=1194180318 ER -