TY - CHAP M1 - Book, Section TI - Evaluation of Donors with Current and/or Past Malignancies A1 - Nair, Gayatri A1 - Nair, Vinay A2 - Molmenti, Ernesto Pompeo PY - 2023 T2 - Molmenti’s Kidney and Pancreas Transplantation: Operative Techniques and Medical Management, 2e AB - Donor transmission of malignancy is a rare but dreaded event as it can progress to metastatic disease in the recipient. The consequences of transmission of cancer are grave due to the recipient’s immunosuppressed status, which can cause rapid spread and even result in death within a short period. Due to the scarcity of organs for transplantation, deliberate use of organs from donors with a history of cancer has been explored. One of the biggest challenges that transplant clinicians face is the decision to transplant organs from a donor with an active or past history of malignant disease. The rate at which different cancers are transmitted vary, and careful selection strategies need to be implemented while assessing a donor with a history of malignancy. Various factors such as the type of tumor, histology, stage at initial diagnosis, disease-free interval, etc., should be considered when assessing donors with a history of malignancy. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/03/29 UR - accesssurgery.mhmedical.com/content.aspx?aid=1194179892 ER -