TY - CHAP M1 - Book, Section TI - Resection of Benign Anterior and Middle Mediastinal Cysts and Tumors A1 - McNamee, Ciaran J. A1 - Hassan, Khalil A. A2 - Sugarbaker, David J. A2 - Bueno, Raphael A2 - Burt, Bryan M. A2 - Groth, Shawn S. A2 - Loor, Gabriel A2 - Wolf, Andrea S. A2 - Williams, Marcia A2 - Adams, Ann PY - 2020 T2 - Sugarbaker’s Adult Chest Surgery, 3e AB - Primary benign anterior and middle mediastinal tumors arise from mediastinal structures either as benign proliferative processes or as a consequence of inflammation. They may also occur as a result of the arrest of embryonic cells traversing this compartment with later tumor growth (germ cell tumors). The majority of benign mediastinal tumors are either cystic or solid; if solid they derive primarily from the thymus, or they extend downward from the superior mediastinum (thyroid substernal goiter), or to a lesser extent they derive from mediastinal mesenchymal tissue. Primary mesenchymal mediastinal tumors represent fewer than 10% of primary mediastinal tumors and have a higher prevalence for malignant potential in children.1 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=1170416532 ER -