TY - CHAP M1 - Book, Section TI - Resection of Substernal Goiter A1 - Farivar, Alexander S. A1 - Razzak, Rene A1 - Vallières, Eric A2 - Sugarbaker, David J. A2 - Bueno, Raphael A2 - Burt, Bryan M. A2 - Groth, Shawn S. A2 - Loor, Gabriel A2 - Wolf, Andrea S. A2 - Williams, Marcia A2 - Adams, Ann PY - 2020 T2 - Sugarbaker’s Adult Chest Surgery, 3e AB - Goiter refers to an enlargement of the thyroid gland. The condition is estimated to affect 5% of the general population. While the definition of substernal goiter varies in the medical literature, goiters usually are considered substernal (also referred to as mediastinal, intrathoracic, or retrosternal) when more than 50% of the thyroid parenchyma is located below the sternal notch. Such tumors have been a focus of interest for surgeons for over 150 years. Klein is credited with being the first to successfully remove a mediastinal goiter in 1820, although the earliest surgical description of mediastinal thyroid extension dates back to Haller in 1749. Today, substernal goiters are treated by a number of different surgical specialists, including thoracic, general, and head and neck surgeons. Goiters account for as many as 10% to 15% of space-occupying mediastinal lesions and are the most common of the superior mediastinal masses. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=1170416258 ER -