TY - CHAP M1 - Book, Section TI - Tumor Biology of Head and Neck Cancer A1 - Chan, Yvonne A1 - Goddard, John C. PY - 2019 T2 - K.J. Lee’s Essential Otolaryngology: Head and Neck Surgery, 12e AB - Results from next-generation sequencing efforts, as well as gene expression analysis has made it obvious that this information will be critical for estimating prognosis and determining appropriate therapy for head and neck cancers. The Cancer Genome Atlas (TCGA), supported by the National Cancer Institute (NCI), has provided detailed information about common gene defects and expression patterns, as well as protein expression profiles found in head and neck squamous cell carcinoma (HNSCC). Although similar data are emerging for some salivary cancer types and molecular analyses of thyroid cancers are rapidly evolving, we will limit discussion here to HNSCC. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=1172372047 ER -