TY  - CHAP
M1  - Book, Section
TI  - Appendix and Small Bowel Diverticula
A1  - Madenci, Arin L.
A1  - Peranteau, William H.
A1  - Smink, Douglas S.
A2  - Zinner, Michael J.
A2  - Ashley, Stanley W.
A2  - Hines, O. Joe
PY  - 2019
T2  - Maingot's Abdominal Operations, 13e
AB  - Although  appendicitis  is  now  well  recognized  as  a  leading  cause  of  surgically  treated  abdominal  pain,  Galen  and  other  early  anatomists  overlooked  the  vermiform  appendix  for  centuries.1  The  Renaissance  artist,  Leonardo  da  Vinci,  became  the  first  to  document  the  existence  of  the  appendix  in  sketches  circa  1500.  Subsequently,  anatomists  da  Carpi2  and  Vesalius3  formally  described  the  appendix  in  the  mid-1500s.  Soon  thereafter,  in  1554,  Fernel  described  the  first  recorded  case  of  disease  of  this  organ:  a  7-year-old  girl  with  diarrhea  was  administered  treatment  with  a  large  quince  fruit,  which  obstructed  the  appendiceal  lumen  after  it  was  ingested.4  She  developed  severe  abdominal  pain  and  died.  Autopsy  showed  the  quince  fruit  obstructing  the  appendiceal  lumen,  with  resultant  appendiceal  necrosis  and  perforation,  thereby  resulting  in  the  first  description,  postmortem,  of  what  would  later  be  known  as  “appendicitis.”  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/23
UR  - accesssurgery.mhmedical.com/content.aspx?aid=1160041771
ER  -