TY - CHAP M1 - Book, Section TI - Carcinoid Tumors and Carcinoid Syndrome A1 - Kim, Teresa S. A1 - Bordeianou, Liliana G. A1 - Hodin, Richard A. A2 - Zinner, Michael J. A2 - Ashley, Stanley W. A2 - Hines, O. Joe PY - 2019 T2 - Maingot's Abdominal Operations, 13e AB - The term “karzinoide” was first used in 1907 by pathologist Siegfried Oberndorfer to describe small intestinal tumors that resembled carcinomas on histology, but behaved less aggressively clinically.1 In the current literature, carcinoids refer to well-differentiated, low-to-intermediate-grade neuroendocrine tumors (NETs) of the bronchopulmonary and gastrointestinal (GI) tracts.2 By definition, NETs are epithelial neoplasms with both neural and endocrine differentiation, which arise from many different cell types of the neuroendocrine system.2 Carcinoids represent a diverse subset of NETs, which exhibit slow growth but variable clinical presentation, growth pattern, and prognosis, depending on anatomic site and cell of origin.2–4 This chapter describes the clinical behavior of GI carcinoids, as well as their diagnosis and management by anatomic site. It concludes with a brief description of metastatic carcinoid and carcinoid syndrome, a rare but potentially life-threatening presentation. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesssurgery.mhmedical.com/content.aspx?aid=1160041611 ER -