TY - CHAP M1 - Book, Section TI - Treatment of Locally Advanced Colorectal Cancer A1 - Bischof, Danielle A. A1 - Efron, Jonathan E. A2 - Morita, Shane Y. A2 - Balch, Charles M. A2 - Klimberg, V. Suzanne A2 - Pawlik, Timothy M. A2 - Posner, Mitchell C. A2 - Tanabe, Kenneth K. PY - 2018 T2 - Textbook of Complex General Surgical Oncology AB - In the United States, rectal cancer is diagnosed in approximately 40,000 individuals annually.1 Although definitions vary, locally advanced rectal cancer generally refers to patients with T3/T4 disease and/or positive lymph nodes.2 In patients with locally advanced rectal cancer, treatment with surgery alone results in substantial risk of local recurrence; therefore, multimodality therapy is recommended. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/15 UR - accesssurgery.mhmedical.com/content.aspx?aid=1145762701 ER -