TY - CHAP M1 - Book, Section TI - Parathyroid Carcinoma A1 - Hansraj, Natasha A1 - Olson, John A. A1 - Turner, Douglas J. A2 - Morita, Shane Y. A2 - Balch, Charles M. A2 - Klimberg, V. Suzanne A2 - Pawlik, Timothy M. A2 - Posner, Mitchell C. A2 - Tanabe, Kenneth K. PY - 2018 T2 - Textbook of Complex General Surgical Oncology AB - Parathyroid carcinoma is a rare malignant neoplasm of the parathyroid causing parathyroid hormone (PTH)–dependent hypercalcemia. Diagnosis is difficult so a high level of suspicion must be maintained, particularly in patients with markedly elevated serum calcium levels, local symptoms, and elevated PTH levels. Presence of these or clinical suspicion at surgery should allow consideration for a more aggressive surgical resection at the initial surgery. In this chapter we review current information on genetics and features of parathyroid carcinoma, and treatment options in the perioperative period. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesssurgery.mhmedical.com/content.aspx?aid=1145757770 ER -