TY - CHAP M1 - Book, Section TI - Metastatic Sarcoma A1 - Liebner, David A. A2 - Morita, Shane Y. A2 - Balch, Charles M. A2 - Klimberg, V. Suzanne A2 - Pawlik, Timothy M. A2 - Posner, Mitchell C. A2 - Tanabe, Kenneth K. PY - 2018 T2 - Textbook of Complex General Surgical Oncology AB - Among individuals diagnosed with bone or soft tissue sarcoma, approximately 10% will have metastatic disease at the time of presentation,1-6 and an estimated 40% will develop metastatic disease during long-term follow-up.7,8 One of the historical challenges associated with managing patients with metastatic bone and soft tissue sarcoma has been the relative rarity of this disease: bone and soft tissue sarcoma represent only 1.1% of adult and 11.8% of pediatric malignancies in the developed world.9 Moreover, bone and soft tissue sarcomas do not behave as a single clinical entity, but actually comprise a heterogeneous group of over 50 distinct malignancies,10 each with important distinguishing features. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=1145757142 ER -