TY - CHAP M1 - Book, Section TI - PARATHYROIDECTOMY A1 - Ellison, E. Christopher A1 - Zollinger, Robert M. PY - 2016 T2 - Zollinger's Atlas of Surgical Operations, 10e AB - Hyperparathyroidism is a common endocrine disorder usually cured by subtotal parathyroidectomy. Parathyroid overactivity documented by appropriate laboratory studies may be associated with general hyperplasia of the parathyroid glands or with an adenoma involving one of the four or more parathyroid glands. Kidney stones, gastrinoma, recurrent pancreatitis, or other conditions are some of the clinical disorders that imply a disorder of the parathyroid glands. Hypercalcemia is discovered as a result of more frequent calcium determinations performed as part of a general screening survey. Hyperparathyroidism is associated with gastrinoma in approximately one-third of patients with the familial multiple endocrine syndrome I (MEN I). A mitogenic cause for the relatively high incidence of recurrent hyperparathyroidism in the familial MEN I syndrome suggests the need for a radical approach, which may consist of total parathyroidectomy with autotransplantation of parathyroid slices into the muscle in the nondominant forearm or removal of 3½ parathyroid glands. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/09/09 UR - accesssurgery.mhmedical.com/content.aspx?aid=1127274394 ER -