TY - CHAP M1 - Book, Section TI - Radiation Therapy for Mesothelioma A1 - Baldini, Elizabeth H. A2 - Sugarbaker, David J. A2 - Bueno, Raphael A2 - Colson, Yolonda L. A2 - Jaklitsch, Michael T. A2 - Krasna, Mark J. A2 - Mentzer, Steven J. A2 - Williams, Marcia A2 - Adams, Ann Y1 - 2015 N1 - T2 - Adult Chest Surgery, 2e AB - Treatment of malignant pleural mesothelioma with radiation therapy (RT) is extremely challenging. The target volume for treatment is very large, involving almost the entire hemithorax, and within and adjacent to this treatment volume, there are many normal structures with low tolerances to radiation. Consequently, it is very difficult to create treatment plans that deliver satisfactorily high doses to the complex target volume yet minimal doses to the adjacent radiosensitive normal organs. This chapter will review the history, current approaches, and future ideas for the treatment of pleural mesothelioma with radiotherapy in definitive, adjuvant, and palliative settings. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/08 UR - accesssurgery.mhmedical.com/content.aspx?aid=1105845142 ER -