TY - CHAP M1 - Book, Section TI - Cardiopulmonary Bypass for Extended Thoracic Resections A1 - Cuadrado, Daniel G. A1 - Leacche, Marzia A1 - Lambright, Eric S. A1 - Byrne, John G. A2 - Sugarbaker, David J. A2 - Bueno, Raphael A2 - Colson, Yolonda L. A2 - Jaklitsch, Michael T. A2 - Krasna, Mark J. A2 - Mentzer, Steven J. A2 - Williams, Marcia A2 - Adams, Ann Y1 - 2015 N1 - T2 - Adult Chest Surgery, 2e AB - Bronchogenic carcinoma remains the most common cause of cancer death in both men and women in the United States. These tumors can exhibit local progression and invasion before metastatic spread has occurred, which does not preclude resection with curative intent. Any contiguous structure within the chest may be involved, with chest wall involvement being the most common. Other potential sites of local invasion include the left atrium, aorta, superior vena cava, vertebral bodies, diaphragm, and esophagus. The increased potential for morbidity and mortality are well documented for these complex extended resections, making appropriate patient selection crucial. Long-term prognosis depends on accurate pretreatment staging to assist in selection of therapy and complete resection. Cardiopulmonary bypass (CPB) may be necessary to allow surgical resection of central, locally advanced malignancies because they involve, or are close to, the heart and/or the great vessels. CPB serves as an alternative to conventional ventilation during extended resections providing oxygenation and hemodynamic support. This chapter will review the role of CPB for the extended resection of lung cancer, as well as the clinical and technical considerations and expected surgical outcomes. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=1105842864 ER -