TY - CHAP M1 - Book, Section TI - Soft Tissue Sarcoma A1 - Doherty, Gerard M. Y1 - 2010 N1 - T2 - Quick Answers Surgery AB - • Soft-tissue sarcomas present as asymptomatic large masses in the extremities or retroperitoneum but may also develop occasionally in the neck or within the abdominal viscera• Originate from a wide variety of mesenchymal cell types and include:-Liposarcoma-Fibrosarcoma-Rhabdomyosarcoma-Leiomyosarcoma-Desmoid tumors• Tumor grade rather than the cell of origin determines natural history• Most soft-tissue sarcomas arise de novo; rarely result from malignant degeneration of a benign lesion• Sarcomas generally metastasize via a hematogenous route, most commonly to the lung• Most important prognostic factors include tumor size and grade SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accesssurgery.mhmedical.com/content.aspx?aid=58101438 ER -