TY - CHAP M1 - Book, Section TI - Mitral Stenosis A1 - Doherty, Gerard M. Y1 - 2010 N1 - T2 - Quick Answers Surgery AB - • Fibrous annulus of mitral valve (MV) is thin, incomplete ring of fibrous tissue• Most MVs have anterior and posterior leaflets, attached by thin fibrous chordae tendineae to papillary muscle• Closed during systole via action of papillary muscle contraction, open during diastole when LA pressure higher than LV pressure• Mitral stenosis (MS) is fibrosis, narrowing of valvular area causing ventricular inflow obstruction during diastole• Early valvular disease of rheumatic fever: Acute inflammatory infiltrate that heals by fibrous organization• Leaflets become fibrotic and thickened causing reduced pliability and surface area• Fusion of leaflets at commissures• Calcification may occur in leaflets• Chordae thickened, shortened, and fibrotic• Mitral complex becomes "fish mouth"• Results in pulmonary congestion, thickening of pulmonary capillaries, intimal fibrosis of arterioles• Pulmonary hypertension progresses with time SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/23 UR - accesssurgery.mhmedical.com/content.aspx?aid=58095073 ER -