TY - CHAP M1 - Book, Section TI - Mitral Regurgitation (MR) A1 - Doherty, Gerard M. Y1 - 2010 N1 - T2 - Quick Answers Surgery AB - • Fibrous annulus of mitral valve (MV) is thin, incomplete ring of fibrous tissue• Most MVs have anterior and posterior leaflets, attached by thin fibrous chordae tendineae to papillary muscle• Closed during systole via action of papillary muscle contraction, open during diastole when LA pressure higher than LV pressure• Etiology includes: -Rheumatic heart disease-Idiopathic MV calcification-Mitral valve prolapse (MVP)-Infective endocarditis-Ischemic MR• Postinfarction papillary muscle rupture: 0.1% of coronary artery disease; congestive heart failure with new murmur days after myocardial infarction• MR results in LA hypertension, resulting in pulmonary congestion, dyspnea, pulmonary hypertension, RV failure• LV is subjected to chronic volume overload causing LV failure (unlike mitral stenosis) SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=58094989 ER -