TY - CHAP M1 - Book, Section TI - Chapter 23. Neoplasms of the Prostate Gland A1 - Cooperberg, Matthew R. A1 - Presti, Joseph C. A1 - Shinohara, Katsuto A1 - Carroll, Peter R. A2 - McAninch, Jack W. A2 - Lue, Tom F. Y1 - 2013 N1 - T2 - Smith & Tanagho's General Urology, 18e AB - The prostate gland is the male organ most commonly afflicted with either benign or malignant neoplasms. McNeal et al (1988) popularized the concept of zonal anatomy of the prostate. Three distinct zones have been identified (Figure 23–1). The peripheral zone accounts for 70% of the volume of the young adult prostate, the central zone accounts for 25%, and the transition zone accounts for 5%. These anatomic zones have distinct ductal systems but, more important, are differentially afflicted with neoplastic processes. Sixty to seventy percent of carcinomas of the prostate (CaP) originate in the peripheral zone, 10–20% in the transition zone, and 5–10% in the central zone (McNeal et al, 1988). Benign prostatic hyperplasia (BPH) uniformly originates in the transition zone (Figure 23–2). SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accesssurgery.mhmedical.com/content.aspx?aid=56945773 ER -