TY - CHAP M1 - Book, Section TI - Chapter 14. Hypercortisolism A1 - Porterfield, John R. A1 - Thompson, Geoffrey B. A2 - Morita, Shane Y. A2 - Dackiw, Alan P. B. A2 - Zeiger, Martha A. Y1 - 2010 N1 - T2 - McGraw-Hill Manual: Endocrine Surgery AB - Hypercortisolism is a disorder characterized by excessive circulating cortisol from either endogenous or exogenous sources, which can cause detrimental changes to nearly every organ system. Collectively, the ravages of hypercortisolism are best classified as Cushing's syndrome (CS). The term Cushing's syndrome is used for all causes of hypercortisolism, and the term Cushing's disease is reserved specifically for cases of pituitary-dependent CS. The most common cause of CS is exogenous administration of glucocorticoids, which are used for their beneficial antiinflammatory, antineoplastic, and immunosuppressive effects. This chapter focuses solely on endogenous CS and is a summary of our recent review at the Mayo Clinic in Rochester, Minnesota.1 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accesssurgery.mhmedical.com/content.aspx?aid=6163237 ER -