TY  - CHAP
M1  - Book, Section
TI  - Chapter 45. Principles of Antimicrobial Therapy and the Clinical Pharmacology of Antimicrobial Drugs
A1  - Aoki, Fred Y.
A2  - Hall, Jesse B.
A2  - Schmidt, Gregory A.
A2  - Wood, Lawrence D.H.
Y1  - 2005
N1  - 
T2  - Principles of Critical Care, 3e
AB  - Rational  antibiotic  use  requires  the  most  specific  diagnosis  that  can  be  made,  knowledge  of  commonly  used  antimicrobial  agents,  and  appropriate  monitoring  of  therapy.Antimicrobial  prophylaxis  against  bacterial  infections  is  indicated  in  selected  patients  undergoing  surgical  procedures  and  in  those  with  cardiac  valvular  disease.When  suspected  infection  threatens  life  or  major  organ  function,  antimicrobial  therapy  should  be  directed  at  all  infectious  possibilities  of  more  than  trivial  probability  until  the  results  of  definitive  investigations  are  available.Knowledge  of  the  clinical  pharmacology  of  antibiotics  commonly  prescribed  in  the  intensive  care  unit  is  essential  for  the  intensivist.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2023/12/05
UR  - accesssurgery.mhmedical.com/content.aspx?aid=2289585
ER  -