TY - CHAP M1 - Book, Section TI - Chapter 22. Ventricular Dysfunction in Critical Illness A1 - Walley, Keith R. A2 - Hall, Jesse B. A2 - Schmidt, Gregory A. A2 - Wood, Lawrence D.H. Y1 - 2005 N1 - T2 - Principles of Critical Care, 3e AB - Understanding cardiovascular dysfunction in a critically ill patient requires consideration of cardiac function and systemic vascular factors controlling venous return.Compression by surrounding structures (cardiac tamponade) and increased afterload must be considered as external causes or contributors to cardiac dysfunction.Decreased ventricular pump function may be due to decreased systolic contractility, increased diastolic stiffness, abnormal heart rate and rhythm, or valvular dysfunction.Management of ventricular dysfunction aims to reverse the cause by optimizing preload and afterload and correcting abnormalities in heart rhythm, valve function, and contractility.Acute reversible contributions to depressed contractility result from ischemia, hypoxemia, acidosis, ionized hypocalcemia and other electrolyte abnormalities, myocardial depressant factors, and hypo- and hyperthermia.Management of acute-on-chronic heart failure progressively includes oxygen; optimizing preload with diuretics, morphine, and nitrates or fluid infusion for hypovolemia; afterload reduction; increasing contractility using catecholamines or phosphodiesterase inhibitors; antiarrhythmic drugs and resynchronization using biventricular pacing; intraaortic balloon counterpulsation; and cardiac transplantation. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2023/10/01 UR - accesssurgery.mhmedical.com/content.aspx?aid=2284545 ER -