TY - CHAP M1 - Book, Section TI - Chapter 11. Nutrition in the Critically Ill A1 - Heyland, Daren K. A1 - McClave, Steve A. A2 - Hall, Jesse B. A2 - Schmidt, Gregory A. A2 - Wood, Lawrence D.H. Y1 - 2005 N1 - T2 - Principles of Critical Care, 3e AB - Nutrients and gastrointestinal structure and function are linked to the pathophysiology of infection, organ dysfunction, and survival in critically ill patients.Nutrition support may both positively and negatively influence the morbidity and mortality of critically ill patients.When considering nutrition support in critically ill patients, enteral nutrition (EN) should be used in preference to parenteral nutrition (PN).Strategies to optimize delivery of EN (e.g., starting EN early, use of a feeding protocol with a high threshold of gastric residual volume, use of prokinetic agents, and use of small bowel feeding) and minimize the risks of EN (e.g., elevation of the head of the bed) should be considered.When initiating EN, PN should not be used in combination with it.For most patient populations in critical care in whom EN is not possible or feasible, standard therapy (IV fluid resuscitation without artificial nutrition support) is preferable to PN for the first 7 to 10 days.When PN is indicated, strategies that maximize the benefit (e.g., supplementing with glutamine) and minimize the risks of PN (e.g., hypocaloric dose, withholding lipids, continued use of EN, and the use of intensive insulin therapy to achieve tight glycemic control) should be considered. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2023/12/02 UR - accesssurgery.mhmedical.com/content.aspx?aid=2282404 ER -