TY - CHAP M1 - Book, Section TI - Chapter 70. Stem Cell–Induced Regeneration of Myocardium A1 - Menasché, Philippe A2 - Cohn, Lawrence H. Y1 - 2012 N1 - T2 - Cardiac Surgery in the Adult, 4e AB - Statistics recently published by the American Heart Association clearly outline the magnitude of the medical and economic problems associated with heart failure.1 It is estimated that 6 million people in the United States are affected by this disease, with a yearly incidence of new episodes (per 1000 people) of 15.2 between 65 and 74 years of age, a figure that is two times higher between 75 and 84 years of age. Still in the United States, the number of hospitalizations for heart failure has thus increased from 877,000 to 1,106,000 in a 10-year time frame (1996–2006), but the problem is now worldwide. The mortality remains high as 80% of men and 70% of women under the age of 65 years in whom heart failure has been diagnosed are expected to die within the next 8 years with a risk of sudden death which is six to nine times that of the general population. As expected, these figures translate into a heavy economic burden with costs estimated to 37 billion dollars in 2008. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/11/06 UR - accesssurgery.mhmedical.com/content.aspx?aid=55931349 ER -