TY - CHAP M1 - Book, Section TI - Acute Plasma Cell-Rich Allograft Rejection A1 - Bijol, Vanesa A2 - Molmenti, Ernesto Pompeo Y1 - 2023 N1 - T2 - Molmenti’s Kidney and Pancreas Transplantation: Operative Techniques and Medical Management, 2e AB - 51-year-old man with end stage polycystic kidney disease. Received a deceased donor kidney transplant 7 years prior to current presentation. Maintained on MMF, prednisone, and tacrolimus. Prior history of rejection. Average creatinine around 1.0 mg/dl. Lost to follow up for 10 months. Admits missing several doses of his immunosuppression medications. Current creatinine 5.5.Allograft biopsy shows extensive interstitial edema and plasma cell-rich infiltrate. Tubules appear distended with flattening of the epithelial layer. These features suggest late acute plasma cell-rich allograft rejection that is associated with under-treatment or poor compliance with immunosuppressive treatment. In general, prognosis is poor. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=1194189260 ER -