TY - CHAP M1 - Book, Section TI - Open Adrenalectomy, Bilateral A1 - Ellison, E. Christopher A1 - Zollinger, Jr., Robert M. A1 - Pawlik, Timothy M. A1 - Vaccaro, Patrick S. A1 - Bitans, Marita A1 - Baker, Anthony S. Y1 - 2022 N1 - T2 - Zollinger’s Atlas of Surgical Operations, 11e AB - The presence of cortical or medullary tumors of either a malignant or benign adenomatous nature is a well-established indication for unilateral adrenalectomy. The indication for bilateral adrenalectomy is much less common. It is occasionally performed to control complex endocrine states after partial or unilateral adrenalectomy has failed to alleviate hyperaldosteronism or hypercortisolism, as in Cushing’s syndrome from bilateral macronodular adrenal hyperplasia or hereditary pheochromocytomas as in multiple endocrine neoplasia type 2 syndrome. Synchronous bilateral adrenalectomy indications include adrenocorticotropic hormone (ACTH)–dependent Cushing’s refractory to other therapy, hereditary pheochromocytomas, or malignancy. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesssurgery.mhmedical.com/content.aspx?aid=1187823385 ER -