TY - CHAP M1 - Book, Section TI - Alcohol and Drugs A1 - Rozycki, Grace F. A1 - Johnson, Laura S. A2 - Feliciano, David V. A2 - Mattox, Kenneth L. A2 - Moore, Ernest E. Y1 - 2020 N1 - T2 - Trauma, 9e AB - KEY POINTSBecause excessive alcohol consumption and/or opioid pain reliever abuse are frequently observed in injured patients, trauma surgeons should know the common substances abused and the interventions to help the patient.An estimated 16 million people in the United States have alcohol use disorder, and an estimated 623,000 of them are adolescents.American College of Surgeons Levels I and II trauma centers are mandated to have protocols in place to assess and screen patients who are at risk for alcohol use disorder.Prescription opioid overdoses and a recent surge in illicit opioid overdoses (heroin and illegally made fentanyl) are interconnected trends that have fueled America’s opioid overdose epidemic.Most illicit drugs exert their initial reinforcing effects by activating reward circuits in the brain similar to those involved in alcohol addiction. Continued drug use impairs brain function by interfering with the capacity to exert self-control over drug-taking behaviors.Treatment for opioid use disorder includes the following medications: methadone, a synthetic opioid agonist that eliminates withdrawal symptoms and relieves drug cravings; buprenorphine, a partial opioid agonist that has weaker activation of opioid receptors but is well tolerated; and naltrexone, an opioid antagonist that blocks the activation of opioid receptors.Surgeons write 36.5% of outpatient prescriptions for opioids, and, therefore, we are uniquely positioned to effect change in the opioid crisis at the local, state, and national levels. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/23 UR - accesssurgery.mhmedical.com/content.aspx?aid=1175140021 ER -