TY - CHAP M1 - Book, Section TI - Management of Malignant Pleural Effusions A1 - Sesti, Joanna A1 - Paul, Subroto A1 - Zellos, Lambros A1 - Bizekis, Costas S. A1 - Zervos, Michael D. A1 - Pass, Harvey I. A2 - Sugarbaker, David J. A2 - Bueno, Raphael A2 - Burt, Bryan M. A2 - Groth, Shawn S. A2 - Loor, Gabriel A2 - Wolf, Andrea S. A2 - Williams, Marcia A2 - Adams, Ann Y1 - 2020 N1 - T2 - Sugarbaker’s Adult Chest Surgery, 3e AB - Malignant pleural effusions (MPEs) cause considerable morbidity for patients afflicted with cancer. Metastatic breast, lung, and ovarian cancers account for the majority of cases. Although there have been no epidemiologic studies, the annual incidence of MPEs in the United States is estimated to be more than 200,000 cases.1,2 Initial malignant diagnosis can be established in 50% to 60% of patients by means of a therapeutic thoracentesis.2,3 However, the malignant effusions often recur, and patients require long-term palliation. The ideal therapy permits expedient, low-cost management of the pleural effusion with minimal morbidity because many of these patients have terminal disease. Nonoperative management of MPEs includes systemic chemotherapy and radiation therapy, as well as several methods of mechanical drainage. Operative management includes drainage through the use of video-assisted thoracic surgery (VATS) techniques combined with pleurodesis, as well as operative placement of indwelling drainage catheters and pleuroperitoneal shunts.3–5 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accesssurgery.mhmedical.com/content.aspx?aid=1170414204 ER -