TY - CHAP M1 - Book, Section TI - Pancoast Tumors A1 - Ibrahim, Kareem A1 - Walsh, Garrett L. A1 - Burt, Bryan M. A2 - Sugarbaker, David J. A2 - Bueno, Raphael A2 - Burt, Bryan M. A2 - Groth, Shawn S. A2 - Loor, Gabriel A2 - Wolf, Andrea S. A2 - Williams, Marcia A2 - Adams, Ann Y1 - 2020 N1 - T2 - Sugarbaker’s Adult Chest Surgery, 3e AB - Superior sulcus tumors, otherwise known as Pancoast tumors, are a unique set of bronchogenic carcinomas. Pancoast tumors account for about 3–5% of all non–small-cell lung cancers (NSCLCs) and have several distinctive features.1 They involve the thoracic inlet and apex of the chest wall and therefore cause a characteristic set of symptoms, depending on which local structures are involved (Fig. 82-1). The 1st and 2nd ribs, 1st and 2nd thoracic vertebral bodies, lower nerve roots of the brachial plexus, sympathetic chain with associated stellate ganglion, and subclavian vessels are all susceptible to local invasion by superior sulcus tumors. Patients can present with a wide variety of symptoms, including chest interscapular or arm pain, paresthesias, hand-muscle wasting, and Horner syndrome. This constellation of symptoms is called Pancoast syndrome; however, a more accurate term would be the Pancoast-Tobias syndrome,2–7 as described by two individuals. Although Henry Pancoast, a radiologist, originally described this constellation of symptoms in 1932, he failed to recognize the pulmonary origin of these tumors. Unaware of Pancoast’s report, Tobias, an Argentine physician, described similar clinical findings and ascribed them to the presence of peripheral lung tumors. It is important to differentiate Pancoast tumor from Pancoast syndrome, as not all superior sulcus tumors cause the symptoms associated with the syndrome and some can be subtle and difficult to diagnose. Pancoast tumors have the same biologic behavior as their histologic counterparts that do not occur in the superior sulcus and, therefore, are diagnosed, staged, and treated the same as other NSCLCs. The symptoms associated with this syndrome are caused by the location of the mass and its anatomic proximity to nearby structures. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesssurgery.mhmedical.com/content.aspx?aid=1170410915 ER -