TY  - CHAP
M1  - Book, Section
TI  - Management of Acute Pancreatitis
A1  - Clancy, Thomas E.
A2  - Zinner, Michael J.
A2  - Ashley, Stanley W.
A2  - Hines, O. Joe
Y1  - 2019
N1  - 
T2  - Maingot's Abdominal Operations, 13e
AB  - Acute  pancreatitis  can  range  from  a  mild,  self-limiting  ­process  that  responds  to  supportive  care  to  severe  disease  with  multiple  organ  failure  and  high  mortality.  Its  incidence  is  ­increasing,1  and  pancreatitis  is  one  of  the  most  common  causes  of  hospital  admission  for  gastrointestinal  illness.2  Although  most  patients  experience  minor  episodes  characterized  by  mild  parenchymal  edema  without  organ  dysfunction,  response  to  conservative  management,  and  ­complete  recovery,3  approximately  20%  to  25%  of  patients  develop  clinically  severe  acute  pancreatitis.  More  severe  episodes  may  progress  to  pancreatic  necrosis,  systemic  inflammatory  response  ­syndrome  (SIRS),  multiorgan  failure,  clinical  deterioration,  and  even  death.4  Historically,  mortality  has  been  up  to  15%  in  the  setting  of  necrotizing  pancreatitis  and  as  high  as  30%  with  infected  pancreatic  necrosis.5  Recent  years  have  seen  advances  in  the  classification  and  management  of  acute  pancreatitis  including  evidence-based  guidelines  and  a  notable  shift  toward  nonoperative  management  of  even  the  most  severe  cases  of  infected  pancreatic  necrosis.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/20
UR  - accesssurgery.mhmedical.com/content.aspx?aid=1160045358
ER  -