TY  - CHAP
M1  - Book, Section
TI  - Ulcerative Colitis
A1  - Lee, Christina W.
A1  - Caldera, Freddy
A1  - Zens, Tiffany
A1  - Kennedy, Gregory D.
A2  - Zinner, Michael J.
A2  - Ashley, Stanley W.
A2  - Hines, O. Joe
Y1  - 2019
N1  - 
T2  - Maingot's Abdominal Operations, 13e
AB  - Ulcerative  colitis  (UC)  is  a  chronic  relapsing  and  remitting  intestinal  disorder  plagued  by  diffuse  and  continuous  mucosal  inflammation  involving  the  rectum,  and  extending  proximally  throughout  the  colon.  As  one  of  two  well-known  disease  types  grouped  under  the  umbrella  of  inflammatory  bowel  diseases  (IBDs),  the  inflammatory  hallmark  in  UC  is  limited  to  the  mucosa.  The  etiology  of  UC  is  not  yet  completely  understood;  however,  research  over  the  last  several  decades  has  led  to  a  better  understanding  of  cellular,  immunological,  and  molecular  mechanisms  involved  in  its  pathogenesis.  Scientists  continue  to  discover  new  and  innovative  approaches  in  the  development  of  potential  biomarkers,  diagnostic  tools,  and  treatment  options  for  patients  with  this  disease.  In  this  chapter,  the  authors  present  a  broad  overview  of  disease  epidemiology,  presentation  and  diagnosis,  and  current  options  for  medical  management  with  a  focus  on  the  surgical  approaches  to  treatment  of  UC.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/16
UR  - accesssurgery.mhmedical.com/content.aspx?aid=1160042416
ER  -