TY - CHAP M1 - Book, Section TI - Ductal Carcinoma in Situ A1 - Flanagan, Meghan A1 - Chen, Yunn-Yi A1 - Hwang, E. Shelley A2 - Morita, Shane Y. A2 - Balch, Charles M. A2 - Klimberg, V. Suzanne A2 - Pawlik, Timothy M. A2 - Posner, Mitchell C. A2 - Tanabe, Kenneth K. Y1 - 2018 N1 - T2 - Textbook of Complex General Surgical Oncology AB - Ductal carcinoma in situ (DCIS) is a preinvasive clinical diagnosis that lies in the continuum between epithelial atypia and invasive cancer. Although it has been recognized and treated for almost three decades, much remains controversial about this disease and its optimal treatment. The incidence of DCIS has increased significantly since it was first described, largely as a consequence of widespread mammographic screening. Accordingly the presentation pattern has changed from a predominantly palpable lesion to one whose first indication is that of an incidentally discovered mammographic abnormality on routine screening examination. Because DCIS is a preinvasive condition with heterogenous potential for invasion, there remains ongoing debate over whether the current treatment recommendations represent overtreatment of some DCIS which may have never resulted in clinical consequences during a patient’s lifetime. This chapter reviews the epidemiology, diagnosis, and treatment of DCIS as well as some future directions for clinical management of the disease. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesssurgery.mhmedical.com/content.aspx?aid=1145760168 ER -