TY - CHAP M1 - Book, Section TI - Resection of Blebs, Bullae, and Giant Bullae A1 - Sonett, Joshua R. A2 - Sugarbaker, David J. A2 - Bueno, Raphael A2 - Colson, Yolonda L. A2 - Jaklitsch, Michael T. A2 - Krasna, Mark J. A2 - Mentzer, Steven J. A2 - Williams, Marcia A2 - Adams, Ann PY - 2015 T2 - Adult Chest Surgery, 2e AB - The pulmonary bleb is a small subpleural collection of air located within the layers of the visceral pleura. Such lesions usually present symptomatically, heralded by a spontaneous pneumothorax. Blebs represent the coalescence of air from small ruptures of terminal alveoli that have dissected through the interstitium to form a small subpleural collection. Lesions that result in spontaneous pneumothorax are located predominantly in the apex of the upper lobe or the apex of the superior segment. Multiple blebs are often identified. Most patients with blebs are without significant underlying lung disease. Pathologically, bleb formation occurs secondary to mechanical stress from increased intrathoracic pressure in the lung tissue that is predisposed to deformation by congenital weakness of the connective tissue. The bleb often forms at the lung apex, where there is increased mechanical stress.1 Surgical therapy thus is oriented to the apex of the lung. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/20 UR - accesssurgery.mhmedical.com/content.aspx?aid=1105843892 ER -