TY - CHAP M1 - Book, Section TI - PYODERMA GANGRENOSUM A1 - Jacks, Stephanie A1 - Dean, Steven M. A2 - Dean, Steven M. A2 - Satiani, Bhagwan A2 - Abraham, William T. PY - 2015 T2 - Color Atlas and Synopsis of Vascular Diseases AB - A 35-year-old woman with no significant medical history presented with a painful ulcer on the right pretibial area. It started as a small pustule that subsequently evolved into a rapidly enlarging ulcer over the course of several weeks. She may have injured the area after falling from her bicycle just prior to the onset of the lesion. A comprehensive review of systems is notable for intermittent crampy abdominal pain and diarrhea for the past year, which had been attributed to irritable bowel syndrome. Laboratory evaluation shows only a mild anemia, but biopsy samples from the terminal ileum are consistent with Crohn disease. A skin biopsy from the edge of the ulcer itself is nondiagnostic. The ulcer improves after initiation of therapy with infliximab for her Crohn disease. Pyoderma gangrenosum is suspected. SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/03/29 UR - accesssurgery.mhmedical.com/content.aspx?aid=1105293006 ER -