TY - CHAP M1 - Book, Section TI - Teratoma A1 - Rescorla, Frederick J. A2 - Ziegler, Moritz M. A2 - Azizkhan, Richard G. A2 - Allmen, Daniel von A2 - Weber, Thomas R. PY - 2014 T2 - Operative Pediatric Surgery, 2e AB - Fifty percent of pediatric germ cell tumors are extragonadal.Teratomas (mature and immature) are the most common germ cell tumor and are benign lesions requiring only complete surgical resection.Yolk sac (endodermal sins) is the predominant prepubertal malignant histology and alpha fetoprotein (AFP) is a marker of disease.Accurate staging is essential as Stage I gonadal tumors are treated without chemotherapy.The survival for malignant germ cell tumors treated with surgery and selective use of chemotherapy is excellent.Current chemotherapy is extremely effective, thus resection of adjacent involved organs or structures is not indicated.Initially unresectable extragonadal tumors treated with neoadjuvant chemotherapy and delayed resection have equivalent survival compared to initial resection. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesssurgery.mhmedical.com/content.aspx?aid=1100439320 ER -