TY - CHAP M1 - Book, Section TI - Retroperitoneal Fibrosis A1 - Doherty, Gerard M. PY - 2010 T2 - Quick Answers Surgery AB - • Retroperitoneal fibrosis characterized by extensive fibrotic encasement of the retroperitoneal tissues• Most common in men over age 50 who have renal failure secondary to obstructive uropathy• Diffuse desmoplastic involvement of the retroperitoneum may alternatively give rise to obstructive jaundice or small or large bowel obstruction• Classic diagnostic triad includes:-Bilateral hydronephrosis/hydroureter-Medial deviation of the ureters-Extrinsic ureteric compression at the L4-5 level• Over 67% of cases are idiopathic• Known etiologies include: -Drugs-Inflammatory disorders-Retroperitoneal hemorrhage-Peri-aneurysmal (abdominal aortic aneurysm [AAA]) inflammation-Irradiation-Urinary extravasation-Cancer• Most common drugs associated with retroperitoneal fibrosis are methsergide and β-blockers• Most common inflammatory condition associated with retroperitoneal fibrosis is Sjögren syndrome SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=58100012 ER -