TY  - CHAP
M1  - Book, Section
TI  - Chapter 6. Medullary Thyroid Carcinoma
A1  - Callender, Glenda G.
A1  - Hu, Mimi I.
A1  - Evans, Douglas B.
A1  - Perrier, Nancy D.
A2  - Morita, Shane Y.
A2  - Dackiw, Alan P. B.
A2  - Zeiger, Martha A.
PY  - 2010
T2  - McGraw-Hill Manual: Endocrine Surgery
AB  - Medullary  thyroid  carcinoma  (MTC)  is  uncommon  and  accounts  for  only  5%  of  all  thyroid  cancers.  MTC  was  first  described  in  1959  as  a  "peculiar"  thyroid  cancer  with  nonfollicular  histology,  amyloid-containing  stroma,  and  a  high  incidence  of  lymph  node  metastases.1  MTC  arises  from  the  parafollicular,  or  calcitonin-secreting,  C  cells  of  the  thyroid  gland.  C  cells  are  neural  crest  cells  that  are  derived  embryologically  from  the  ultimobranchial  bodies  and  migrate  to  the  thyroid  gland.  They  are  found  throughout  the  thyroid  but  often  concentrate  in  the  uppermost  third  of  the  thyroid  lobes;  therefore,  MTC  usually  originates  in  this  region2  (Figure  6-1).  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesssurgery.mhmedical.com/content.aspx?aid=6162569
ER  -