TY - CHAP M1 - Book, Section TI - Chapter 17. High-Risk Lesions: ALH/LCIS/ADH A1 - Smart, Chanel E. A1 - Smart, Chanel E. A1 - Furnival, Colin M. A1 - Furnival, Colin M. A1 - Lakhani, Sunil R. A1 - Lakhani, Sunil R. A2 - Kuerer, Henry M. PY - 2010 T2 - Kuerer's Breast Surgical Oncology AB - The multistep model for breast carcinogenesis suggests that invasive carcinomas arise from preinvasive "hyperplastic" and neoplastic proliferations. These early proliferative lesions have taken on greater significance as a result of the mammographic screening and detection programs. Pathologists are encountering these proliferative lesions with increasing frequency, and this has highlighted deficiencies in classification systems as well as a lack of data on natural history, making clinical management a challenge. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accesssurgery.mhmedical.com/content.aspx?aid=6408548 ER -